A molecular sensor, also known as a chemosensor or probe, is a molecular or supramolecular-based system that is able to transform probe–analyte interactions into a signal which allows analyte sensing. The most common output signals are usually optical or electrochemical changes. The design of these molecular sensors and probes has advanced and gained importance in the last years due to the progress made in the knowledge on the preparation of host–guest complexes and on studies on how this interaction can be used for the design of selective molecular probes. This is a very interdisciplinary filed that in many cases involves organic or inorganic synthesis, photo-physical studies, and analytical applications.
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